Skip to main content

Table 2 Details of supervised and home-based exercise prescription for participants on a 2-week chemotherapy cycle protocol

From: Study protocol of the Aerobic exercise and CogniTIVe functioning in women with breAsT cancEr (ACTIVATE) trial: a two-arm, two-centre randomized controlled trial

Cycle Week Supervised Program Home-based Program
   Freq. Duration (minutes) Intensity (% HRR) Freq. Duration (minutes) Intensity (RPE)
1 1 3 20–25 50–55a, 55–60 0 0 0
2 3 25–30 55–65 0 0 0
2 3 3 25–35 50–55a, 60–65 1 15–20 12–13
4 3 25–35 60–65, VT 1 15–20 12–13
3 5 3 35–40 55–60a, 60–65 1 15–20 12–13
6 3 25–35 65–70, HIIT 1 20–30 12–13
4 7 3 35–40 55–60a, 65–70 1 20–30 12–13
8 3 20–40 65–70, HIIT 1 20–30 12–13
5 9 3 40 55–60a, 65–70 1 20–30 12–13
10 3 20–35 70–75, VT/HIITb 1 20–30 12–13
6 11 3 40 55–60a, 65–70 1 20–30 12–13
12 3 20–35 70–75, VT/HIITb 1 20–30 12–13
7 13 3 40 55–60a, 65–70 1 20–30 12–13
14 3 20–35 70–75, VT/HIITb 1 20–30 12–13
8 15 3 40 55–60a, 65–70 1 20–30 12–13
16 3 25–35 70–75, VT/HIITb 1 20–30 12–13
  1. Freq. Frequency, HIIT high-intensity interval training session (10–16 bouts of 30 s at 100% peak workload and 1–2 min of active recovery), HRR Heart rate reserve, RPE Rating of perceived exertion, VT ventilatory threshold session (4 bouts of 5 min at VT and 3 min of active recovery).
  2. aThe first exercise session immediately after chemotherapy infusion is prescribed at 50–55% HRR (first two cycles) and 50–60% HRR (remaining cycles) (i.e., 5–10% reduction in workload). bAfter Cycle 5, VT and HIIT sessions are prescribed based on participants' preference. Participants perform a 5-min warm-up before and 5-min cool-down after each exercise session