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Table 3 Odds ratios (women vs men) for stage IV disease by screening status and diagnostic delay

From: Gender differences in stage at diagnosis and preoperative radiotherapy in patients with rectal cancer

  Stage IV
Unadjusteda   Adjusteda,b  
OR (95% CI) p-value OR (95%) p-value
Screening
 No 1.23 (0.67–2.16) 0.48 1.04 (0.61–1.77) 0.89
 Yes 6.9 (0.88–53.96) 0.06 7.20 (0.93–55.79) 0.05
 Unknown 3.05 (2.27–4.11) < 0.0005 4.26 (3.18–5.72) < 0.0005
Diagnostic delay
  ≤ 3 months 1.07 (0.56–2.08) 0.83 0.95 (0.49–1.85) 0.99
  > 3 months 6.25 (1.57–24.89) 0.009 5.05 (1.18–21.58) 0.03
 Unknown 3.61 (1.19–10.96) 0.02 3.91 (1.13–13.53) 0.03
  1. aWe used generalized estimating equations to estimate the women-to-men odds ratios (ORs) in each stratum of the variables with significant multiplicative interactions
  2. bAdjusted for age, comorbidity, and preoperative radiotherapy