Table 1 Study outcomes and selected clinical characteristics by gender
Men N = 522 | Women N = 248 | p-value1 | |
|---|---|---|---|
Pathological stage | |||
0, I | 192 (36.8) | 100 (40.3) | 0.09 |
II | 144 (27.6) | 53 (21.4) | |
III | 152 (29.1) | 69 (27.8) | |
IV | 34 (6.5) | 26 (10.5) | |
Preoperative radiotherapy | |||
No | 233 (44.6) | 124 (50.0) | 0.16 |
Yes | 289 (55.4) | 124 (50.0) | |
Unknown | 25 (4.8) | 17 (6.9) | |
Age | |||
65 years | 221 (42.3) | 108 (43.5) | 0.682 |
65–80 years | 245 (46.9) | 105 (42.3) | |
> 80 years | 56 (10.7) | 35 (14.1) | |
Charlson index | |||
0 | 258 (49.4) | 165 (66.5) | < 0.0005 |
≥ 1 | 264 (50.6) | 83 (33.5) | |
Screening | |||
No | 429 (82.2) | 201 (81.0) | 0.48 |
Yes | 68 (13.0) | 30 (12.1) | |
Unknown | 25 (4.8) | 17 (6.9) | |
Diagnostic delay | |||
≤ 3 months | 374 (71.6) | 155 (62.5) | 0.02 |
> 3 months | 83 (15.9) | 59 (23.8) | |
Unknown | 65 (12.5) | 34 (13.7) | |
Distance from anal verge | |||
< 5 cm | 100 (19.2) | 57 (23.0) | 0.16 |
5–10 cm | 218 (41.8) | 83 (33.5) | |
> 10 cm | 167 (32.0) | 90 (36.3) | |
Unknown | 37 (7.1) | 18 (7.3) | |
Histological classification | |||
Adenocarcinoma | 474 (90.8) | 208 (83.9) | 0.04 |
Mucinous adenocarcinoma | 18 (3.4) | 14 (5.6) | |
Undifferentiated carcinomas | 6 (1.1) | 4 (1.6) | |
Unknown | 24 (4.6) | 22 (8.9) | |
Tumor depth (cT) | |||
cT1 - cT2 | 91 (17.4) | 55 (22.2) | < 0.0005 |
cT3 | 273 (52.3) | 120 (48.4) | |
cT4 | 28 (5.4) | 34 (13.7) | |
Unknown | 130 (24.9) | 39 (15.7) | |