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Table 1 Study outcomes and selected clinical characteristics by gender

From: Gender differences in stage at diagnosis and preoperative radiotherapy in patients with rectal cancer

  Men N = 522 Women N = 248 p-value1
Pathological stage
 0, I 192 (36.8) 100 (40.3) 0.09
 II 144 (27.6) 53 (21.4)  
 III 152 (29.1) 69 (27.8)  
 IV 34 (6.5) 26 (10.5)  
Preoperative radiotherapy
 No 233 (44.6) 124 (50.0) 0.16
 Yes 289 (55.4) 124 (50.0)  
 Unknown 25 (4.8) 17 (6.9)  
Age
 65 years 221 (42.3) 108 (43.5) 0.682
 65–80 years 245 (46.9) 105 (42.3)  
  > 80 years 56 (10.7) 35 (14.1)  
Charlson index
 0 258 (49.4) 165 (66.5) < 0.0005
  ≥ 1 264 (50.6) 83 (33.5)  
Screening
 No 429 (82.2) 201 (81.0) 0.48
 Yes 68 (13.0) 30 (12.1)  
 Unknown 25 (4.8) 17 (6.9)  
Diagnostic delay
  ≤ 3 months 374 (71.6) 155 (62.5) 0.02
  > 3 months 83 (15.9) 59 (23.8)  
 Unknown 65 (12.5) 34 (13.7)  
Distance from anal verge
  < 5 cm 100 (19.2) 57 (23.0) 0.16
 5–10 cm 218 (41.8) 83 (33.5)  
  > 10 cm 167 (32.0) 90 (36.3)  
 Unknown 37 (7.1) 18 (7.3)  
Histological classification
 Adenocarcinoma 474 (90.8) 208 (83.9) 0.04
 Mucinous adenocarcinoma 18 (3.4) 14 (5.6)  
 Undifferentiated carcinomas 6 (1.1) 4 (1.6)  
 Unknown 24 (4.6) 22 (8.9)  
Tumor depth (cT)
 cT1 - cT2 91 (17.4) 55 (22.2) < 0.0005
 cT3 273 (52.3) 120 (48.4)  
 cT4 28 (5.4) 34 (13.7)  
 Unknown 130 (24.9) 39 (15.7)  
  1. Numbers in parentheses correspond to percentages
  2. 1 Pearson chi-square test
  3. 2 Chi-square test for trend