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Fig. 4 | BMC Cancer

Fig. 4

From: PARP inhibitors combined with ionizing radiation induce different effects in melanoma cells and healthy fibroblasts

Fig. 4

Cell migration analysis in melanoma cells. a Representative scratch area of melanoma cell line BIMA without treatment a, treated with 2 Gy IR b, treated with 50 nmol/l talazoparib c and with combined treatment of 50 nmol/l talazoparib and 2 Gy IR d over time (0 h, 24 h, 48 h). e Decrease of the relative scratch area of melanoma cell line BIMA w/o talazoparib treatment, w/o 2 Gy IR within 48 h; each value represents mean ± SD (n = 4). f Decrease of the relative scratch area of melanoma cell line BIMA w/o niraparib treatment, w/o 2 Gy IR within 48 h; each value represents mean ± SD (n = 4)

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