Variable | Group | Statistics | Post-hoca | ||
---|---|---|---|---|---|
Noncancer control | Breast cancer group not receiving chemotherapy | Breast cancer group receiving chemotherapy | |||
N = 29 | N = 55 | N = 32 | |||
Marital status (married) | 25 (86.21) | 41 (74.55) | 26 (81.25) | χ2 = 1.68; p = 0.433 | – |
Cancer stage | |||||
 0 | – | 5 (9.26) | 0 (0) | – | – |
 1 |  | 15 (27.78) | 9 (28.13) |  |  |
 2 |  | 25 (46.30) | 17 (53.13) |  |  |
 3 |  | 8 (14.81) | 6 (18.75) |  |  |
Age (years) | 47.59 (11.09) | 52.40 (11.06) | 49.56 (10.72) | F = 1.96; p = 0.146 | – |
Education (years) | 12.79 (3.70) | 10.59 (4.37) | 11.81 (2.95) | F = 3.26; p = 0.042* | 1 > 2 |
Duration of completion of chemotherapy (days) | – | – | 129.68 (50.57) | – | – |
Type of chemotherapy | |||||
 Anthracyclines | – | – | 29 (90.63) | – | – |
 Taxanes | – | – | 22 (68.75) | – | – |
 Other DNA synthesis inhibitors | – | – | 29 (90.63) | – | – |
 Other microtubule inhibitors | – | – | 0 (0) | – | – |
Tumor mass (cm3) | – | – | 6.36 (9.68) |  |  |
Pro-inflammatory (pg/mL) | |||||
 IL-1β | 0.97 (0.49) | 0.91 (0.80) | 0.70 (0.49) | H = 6.63; p = 0.036* | 1 = 2 = 3 |
 IL-2 | 1.70 (1.30) | 1.53 (1.22) | 0.96 (0.84) | H = 9.46; p = 0.009** | 1 > 3 |
 IL-6 | 2.41 (1.67) | 1.83 (1.88) | 1.72 (1.97) | H = 7.42; p = 0.025* | 1 = 2 = 3 |
 IL-12p70 | 3.35 (1.96) | 2.57 (1.77) | 2.01 (1.45) | H = 8.59; p = 0.014* | 1 > 3 |
 IL-17A | 7.94 (3.78) | 7.17 (3.73) | 5.16 (2.52) | H = 11.90; p = 0.003** | 1 = 2 > 3 |
 IFNγ | 12.83 (7.14) | 8.71 (5.80) | 7.26 (4.27) | H = 13.88; p = 0.001*** | 1 > 2 = 3 |
 TNFα | 5.74 (2.79) | 5.41 (2.97) | 5.17 (2.55) | H = 1.34; p = 0.513 | – |
Anti-inflammatory (pg/ml) | |||||
 IL-4 | 15.14 (10.10) | 13.06 (11.58) | 10.09 (7.16) | H = 4.54; p = 0.103 | – |
 IL-5 | 1.73 (1.19) | 1.80 (1.30) | 1.25 (0.98) | H = 4.40; p = 0.111 | – |
 IL-10 | 6.41 (4.86) | 6.02 (4.75) | 3.69 (3.46) | H = 8.02; p = 0.018* | 1 = 2 = 3 |
 IL-13 | 4.81 (2.67) | 3.36 (2.89) | 3.12 (4.19) | H = 12.66; p = 0.002** | 1 = 2 = 3 |
PHQ (depression) | 2.00 (2.58) | 5.42 (4.72) | 3.28 (2.67) | F = 8.54; p < 0.001*** | 2 > 1 = 3 |