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Table 5 Multivariate analysis of baseline parameters associated with OS

From: Education level as a predictor of survival in patients with multiple myeloma

Variables OS
HR (95% CI) P
All patients
 Age (per year of age) 1.03 (1.00–1.05) 0.028
 Education level: high vs low 0.32 (0.19–0.56) < 0.001
 LDH: ≥240 vs < 240 U/L 1.86 (1.18–2.94) 0.008
 Cytogenetics: high risk vs standard risk 2.01 (1.32–3.06) 0.001
 Comorbidity: yes vs no 2.01 (1.25–3.23) 0.004
 Regular treatment: no vs yes 1.73 (1.08–2.77) 0.024
Patients < 60 years
 Education level: high vs low 0.30 (0.14–0.62) 0.001
 Cytogenetics: high risk vs standard risk 2.37 (1.30–4.32) 0.005
 Regular treatment: no vs yes 2.17 (1.08–4.38) 0.030
Patients ≥ 60 years
 Education level: high vs low 0.26 (0.11–0.62) 0.002
 LDH: ≥240 vs < 240 U/L 2.27 (1.24–4.18) 0.008
 Cytogenetics: high risk vs standard risk 1.84 (1.01–3.33) 0.045
 Comorbidity: yes vs no 3.16 (1.32–7.55) 0.010
  1. OS overall survival, HR hazard ratio, CI confidence interval, LDH lactate dehydrogenase