Cancer type | Expression | Micro-RNAs | Targets | Functions | References |
---|---|---|---|---|---|
non-small cell lung cancer | down-regulation | – | MMP2; MMP9; N-cadherin; E-cadherin | epithelial-mesenchymal transition (EMT) | [19] |
hepatocellular carcinoma | up-regulation | – | Vimentin; E-Cadherin | migration, invasion | [17] |
 | up-regulation | – | Bcl-2; Bax; MEK; ERK; JNK; P38; | cell invasion, proliferation and migration and apoptosis | [14] |
 | up-regulation | – |  | cell proliferation and migration | [15] |
 | up-regulation | – | – | cell growth, migration and invasion | [16] |
osteosarcoma | up-regulation | – | ZEB1 | apoptosis | [11] |
papillary thyroid cancer | down-regulation | – | AKT; MEK; ERK; JNK; P38; | proliferation, migration and invasiveness | [24] |
 | down-regulation | – | MAPK; PI3K-AKT | cell growth, cycle and apoptosis | |
 | up-regulation | – | Raf; MEK; ERK; | cell autophagy | [27] |
colorectal cancer | up-regulation | – | Vimentin; E-Cadherin; MEK; ERK; | epithelial-mesenchymal transition (EMT) | [34] |
 | up-regulation | miR-203 | CSE1L | proliferation and invasion; cell sensitivity to adriamycin (ADR) | [42] |
bladder cancer | down-regulation | – | – | apoptosis and migration | [30] |
Malignant Melanoma | up-regulation | Â | AKT; MEK; ERK; JNK; P38; | cell proliferation and migration | [31] |
breast cancer | up-regulation | – | Bcl-2; Bax; PARP; Cleaved-caspase3 | cell proliferation and invasion | [33] |
 | up-regulation | – | Vimentin; E-Cadherin; MMP2; MMP9; MMP14 | cell migration and invasion | [32] |
clear cell renal cell carcinoma | up-regulation | – | caspase3; caspase9; CDK4; CDK6 | cell growth, cycle and apoptosis | [18] |