Table 2 Correlation between the expression of the insulin-like growth factor receptor 1 (IGF1R) and the insulin receptor (IR) in tumor cells
From: Questioning the IGF1 receptor’s assigned role in CRC – a case for rehabilitation?
IR expression in tumor cells | IR expression in tumor vessels | ||||
|---|---|---|---|---|---|
negative | positive | low | high | ||
Cytoplasmic IGF1R expression | n (%) | n (%) | n (%) | n (%) | p-Value |
low (HScore < 90) | 217 (33.0) | 440 (67.0) | 287 (43.7) | 370 (56.3) | < 0.001 |
high (HScore ≥ 90) | 188 (23.5) | 613 (76.5) | 230 (28.7) | 570 (71.3) | |
Membranous IGF1R expression | |||||
low (HScore ≤ 10) | 224 (29.9) | 526 (70.1) | 319 (42.5) | 431 (57.5) | < 0.001 |
high (HScore > 10) | 181 (25.6) | 527 (74.4) | 198 (28.0) | 509 (72.0) | |