Fig. 1
From: Questioning the IGF1 receptor’s assigned role in CRC – a case for rehabilitation?
Insulin-like growth factor 1 receptor (IGF1R) immunoreactivity. Colorectal carcinoma samples showing (a) strong cytoplasmic (2+) and strong membranous (2+) staining, (b) weak (1+) cytoplasmic and weak (1+) membranous staining, (c) weak cytoplasmic (1+) and no (0) membranous staining, and (d) neither cytoplasmic nor membranous insulin-like growth factor 1 receptor (IGF1R) staining. IGF1R expression in endometrial cells (proliferative phase) served as a positive control (e) and the omission of the primary antibody served as the negative control (f). Original magnification a-d: 400x