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Fig. 8 | BMC Cancer

Fig. 8

From: A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway

Fig. 8

PT activates p38 MAPK and inhibits AKT phosphorylation. a-c HT-29 b-d SW620 cells exposed to different concentration of PT for 24 h at 37 °C. Total cell lysates were prepared and immunoblotted with the indicated antibodies. Density of the protein bands of three independent experiments were quantified and expressed as relative protein expression to actin. The bar graphs are presented as mean ± SD of three independent experiments. * < p < 0.05, **p < 0.01, ***p < 0.001 vs control. Full Length blots were presented in Supplementary Figure S3

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