Table 2 The independent prognostic clinical factors according to univariate and multivariate Cox regression analyses

Age (years, mean ± SD)

65.40 ± 13.21

0.989

0.973–1.006

2.26E-01

–

–

–

Gender (Male/Female)

198/169

1.485

0.967–2.283

6.93E-02

–

–

–

Pathologic M (M0/M1/−)

279/40/48

3.712

2.230–6.180

6.40E-08

3.786

1.168–12.265

2.65E-02

Pathologic N (N0/N1/N2)

223/90/54

2.053

1.588–2.654

1.07E-08

1.404

0.755–2.609

2.83E-01

Pathologic T (T1/T2/T3/T4)

10/66/252/39

2.687

1.774–4.071

7.12E-06

2.159

1.116–4.176

2.23E-02

Pathologic stage (I / II / III / IV)

66/144/108/40

1.982

1.550–2.535

2.45E-08

0.733

0.313–1.716

4.75E-01

Lymphovascular invasion (Yes/No/−)

121/213/33

1.968

1.266–3.059

2.19E-03

0.709

0.357–1.407

3.25E-01

Vascular invasion (Yes/No/−)

68/250/49

2.211

1.361–3.589

1.00E-03

0.983

0.464–2.079

9.63E-01

PS model status (High/ Low)

183/184

4.522

2.740–7.465

1.06E-10

4.053

2.161–7.601

1.29E-05

Tumor status (Recurrence/Free)

88/279

–

–

–

–

–

–

Disease free survival time (months, mean ± SD)

28.30 ± 25.41

–

–

–

–

–

–