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Table 2 The independent prognostic clinical factors according to univariate and multivariate Cox regression analyses

From: Prognosis prediction model based on competing endogenous RNAs for recurrence of colon adenocarcinoma

Clinical characteristics TCGA (N = 367) Uni-variables cox Multi-variables cox
HR 95%CI P HR 95%CI P
Age (years, mean ± SD) 65.40 ± 13.21 0.989 0.973–1.006 2.26E-01
Gender (Male/Female) 198/169 1.485 0.967–2.283 6.93E-02
Pathologic M (M0/M1/−) 279/40/48 3.712 2.230–6.180 6.40E-08 3.786 1.168–12.265 2.65E-02
Pathologic N (N0/N1/N2) 223/90/54 2.053 1.588–2.654 1.07E-08 1.404 0.755–2.609 2.83E-01
Pathologic T (T1/T2/T3/T4) 10/66/252/39 2.687 1.774–4.071 7.12E-06 2.159 1.116–4.176 2.23E-02
Pathologic stage (I / II / III / IV) 66/144/108/40 1.982 1.550–2.535 2.45E-08 0.733 0.313–1.716 4.75E-01
Lymphovascular invasion (Yes/No/−) 121/213/33 1.968 1.266–3.059 2.19E-03 0.709 0.357–1.407 3.25E-01
Vascular invasion (Yes/No/−) 68/250/49 2.211 1.361–3.589 1.00E-03 0.983 0.464–2.079 9.63E-01
PS model status (High/ Low) 183/184 4.522 2.740–7.465 1.06E-10 4.053 2.161–7.601 1.29E-05
Tumor status (Recurrence/Free) 88/279
Disease free survival time (months, mean ± SD) 28.30 ± 25.41
  1. TCGA The Cancer Genome Atlas, HR hazard ratio, CI confidence interval, SD standard deviation