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Table 1 The optimum prognostic signature DERs identified by L1 penalized estimation based Cox-Proportional Hazards (Cox-PH) model

From: Prognosis prediction model based on competing endogenous RNAs for recurrence of colon adenocarcinoma

Symbol Chromosome location Type Multi-variate Cox regression analysis Lasso coefficient
HR 95%CI P value
Protective RNAs
hsa-mir-105-1 Xq28 miRNA 0.629 0.444–0.891 4.990E-02 −0.034
hsa-mir-3609 7q22.1 miRNA 0.635 0.486–0.831 9.340E-04 −0.394
 MMAA 4q31.21 mRNA 0.680 0.475–0.974 3.520E-02 −0.781
Risky RNAs
LINC00115 1p36.33 lncRNA 1.692 1.103–2.595 1.602E-02 0.238
NCBP2-AS1 3q29 lncRNA 2.121 1.450–3.104 1.080E-04 0.122
hsa-mir-34c 11q23.1 miRNA 1.150 1.013–1.304 3.019E-02 0.039
hsa-mir-363 Xq26.2 miRNA 1.250 1.121–1.395 6.490E-05 0.243
hsa-mir-4709 14q24.3 miRNA 1.480 1.200–1.825 2.510E-04 0.635
hsa-mir-891a Xq27.3 miRNA 1.165 1.028–1.320 1.695E-02 0.196
ALOX15 17p13.2 mRNA 1.495 1.229–1.818 5.660E-05 0.395
ERVMER34–1 4q12 mRNA 1.259 1.058–1.497 9.378E-03 0.305
GRAP 17p11.2 mRNA 1.782 1.242–2.556 1.704E-03 0.542
KCP 7q32.1 mRNA 1.258 1.158–1.652 9.050E-03 0.231
NKAIN4 20q13.33 mRNA 2.221 1.396–3.533 7.510E-04 0.220
PADI1 1p36.13 mRNA 1.326 1.159–1.517 3.970E-05 0.373
SIX4 14q23.1 mRNA 1.543 1.026–2.319 3.713E-02 0.423
SLC16A8 22q13.1 mRNA 2.161 1.303–3.583 2.821E-03 0.881
  1. HR hazard ratio, CI confidence interval