Table 3 Calibration assessment of the EGFR mutation predictive model
Group a | N | Predicted EGFR mutation | Observed EGFR mutation | ||||
|---|---|---|---|---|---|---|---|
Number | Mean | (min-max) | Number | Proportion | (95% CI) | ||
Development group | |||||||
1 | 254 | 17 | 0.07 | (0.04–0.08) | 18 | 0.07 | (0.04–0.11) |
2 | 228 | 24 | 0.11 | (0.09–0.11) | 14 | 0.06 | (0.04–0.10) |
3 | 282 | 41 | 0.14 | (0.11–0.15) | 41 | 0.15 | (0.11–0.19) |
4 | 234 | 67 | 0.28 | (0.16–0.38) | 80 | 0.34 | (0.28–0.40) |
5 | 178 | 101 | 0.57 | (0.39–0.62) | 96 | 0.54 | (0.47–0.61) |
Validation group | |||||||
1 | 100 | 7 | 0.07 | (0.04–0.08) | 7 | 0.07 | (0.03–0.14) |
2 | 100 | 10 | 0.10 | (0.09–0.11) | 9 | 0.09 | (0.05–0.16) |
3 | 133 | 20 | 0.15 | (0.11–0.15) | 15 | 0.11 | (0.07–0.18) |
4 | 59 | 14 | 0.23 | (0.16–0.29) | 13 | 0.22 | (0.13–0.34) |
5 | 97 | 48 | 0.50 | (0.31–0.62) | 46 | 0.47 | (0.38–0.57) |