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Table 2 Single and multi-variable analysis

From: Development and validation of a predictive model for estimating EGFR mutation probabilities in patients with non-squamous non-small cell lung cancer in New Zealand

 

Single factor analysis

Multivariable analysis

Mutation positive

p-value

OR

(95% CI)

p-value

N

%

Total

249

21.17

    

Age at diagnosis

  

0.063

   

  < 50 year

21

28.38

    

 50–59 year

37

19.89

    

 60–69 year

60

16.62

    

 70–79 year

97

23.54

    

  > =80 year

34

23.78

    

Sex

  

< 0.001

   

 Male

77

15.01

 

1

  

 Female

172

25.94

 

1.5

(1.1–2.1)

0.014

Ethnicity

  

< 0.001

   

 NZ European

105

15.4

 

1

  

 NZ Maori

16

9.14

 

0.7

(0.4–1.2)

0.201

 Pacific

35

27.56

 

1.6

(1.0–2.6)

0.052

 Asian

87

49.15

 

2.8

(1.8–4.2)

< 0.001

 Other & Unknown

6

40

 

2.5

(0.8–7.5)

0.118

Smoking status

  

< 0.001

   

 Current smoker

19

7.2

 

1

  

 Ex-smoker

85

14.07

 

2

(1.2–3.5)

0.008

 Non-smoker

145

47.08

 

6.7

(3.9–11.7)

< 0.001

Extent

  

0.005

–

  

 Localised

42

32.31

    

 Adjacent or regional

50

18.8

    

 Distant spread

106

18.89

    

 Unknown

51

23.29

    

Histology

  

< 0.001

–

  

 Adenocarcinoma

238

23.24

    

 Other

11

7.24

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