Table 2 Verification of NGS panel using ddPCR as a gold standard
From: Efficient mutation screening for cervical cancers from circulating tumor DNA in blood
Positive | Negative | Total | Sensitivity | Specificity | |
|---|---|---|---|---|---|
PIK3CA(E545K) | |||||
Positive | 8 | 1 | 9 | 88.9% | 100% |
Negative | 0 | 3 | 3 | ||
Total | 8 | 4 | 12 | ||
KRAS(G12D) | |||||
Positive | 9 | 0 | 9 | 100% | 100% |
Negative | 0 | 3 | 3 | ||
Total | 9 | 3 | 12 | ||