Table 2 The subgroups analysis of clinical characteristics between low- and high- risk groups

TCGA

level

High_risk

Low_risk

p

test

n

40

40

age (%)

Age < 60

16 (40.0)

20 (50.0)

0.500

Chisq Test

Age > =60

24 (60.0)

20 (50.0)

gender (%)

FEMALE

14 (35.0)

21 (52.5)

0.176

Chisq Test

MALE

26 (65.0)

19 (47.5)

M (%)

m0

25 (64.1)

26 (66.7)

0.588

Chisq Test

m1

3 (7.7)

1 (2.6)

mx

11 (28.2)

12 (30.8)

N (%)

n0

25 (64.1)

27 (67.5)

0.935

Chisq Test

nx

14 (35.9)

13 (32.5)

T (%)

t2

5 (12.5)

9 (22.5)

0.440

Chisq Test

t3

18 (45.0)

14 (35.0)

t4

17 (42.5)

17 (42.5)

stage (%)

N/A

1 (2.5)

0 (0.0)

0.481

Chisq Test

Stage II

20 (50.0)

19 (47.5)

Stage III

16 (40.0)

20 (50.0)

Stage IV

3 (7.5)

1 (2.5)

histological_type (%)

Epithelioid Cell

10 (25.0)

3 (7.5)

0.010

Chisq Test

Spindle Cell

9 (22.5)

21 (52.5)

Spindle Cell|Epithelioid Cell

21 (52.5)

16 (40.0)

vital_status (%)

ALIVE

23 (57.5)

34 (85.0)

0.014

Chisq Test

DEAD

17 (42.5)

6 (15.0)

subtype (%)

subtype1

3 (7.5)

12 (30.0)

0.000

Chisq Test

subtype2

9 (22.5)

14 (35.0)

subtype3

10 (25.0)

12 (30.0)

subtype4

18 (45.0)

2 (5.0)

chromosome.3.status (%)

Disomy 3

12 (30.0)

26 (65.0)

0.004

Chisq Test

Monosomy 3

28 (70.0)

14 (35.0)

GEO

level

High_risk

Low_risk

p

test

n

14

14

Age (%)

Age < 60

5 (35.7)

7 (50.0)

0.703

Fisher exact test

Age > =60

9 (64.3)

7 (50.0)

vital_status (%)

ALIVE

3 (21.4)

9 (64.3)

0.052

Fisher exact test

DEAD

11 (78.6)

5 (35.7)

Chromosome.3.status (%)

Disomy 3

4 (28.6)

10 (71.4)

0.053

Fisher exact test

Monosomy 3

10 (71.4)

4 (28.6)

Metastasis (%)

No

5 (35.7)

10 (71.4)

0.130

Fisher exact test

Yes

9 (64.3)

4 (28.6)