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Table 1 Clinicopathological characteristics of C1/2 molecular subtypes

From: The prognostic values of m6A RNA methylation regulators in uveal melanoma

TCGA

level

C1

C2

p

test

n

 

61

19

  

age (%)

Age < 60

27 (44.3)

9 (47.4)

1.000

Chisq Test

Age > =60

34 (55.7)

10 (52.6)

  

gender (%)

FEMALE

25 (41.0)

10 (52.6)

0.529

Chisq Test

MALE

36 (59.0)

9 (47.4)

  

M (%)

m0

39 (66.1)

12 (63.2)

0.972

Chisq Test

m1

3 (5.1)

1 (5.3)

  

mx

17 (28.8)

6 (31.6)

  

N (%)

n0

40 (65.6)

12 (66.7)

1.000

Chisq Test

nx

21 (34.4)

6 (33.3)

  

T (%)

t2

9 (14.8)

5 (26.3)

0.225

Chisq Test

t3

23 (37.7)

9 (47.4)

  

t4

29 (47.5)

5 (26.3)

  

stage (%)

N/A

1 (1.6)

0 (0.0)

0.238

Chisq Test

Stage II

26 (42.6)

13 (68.4)

  

Stage III

31 (50.8)

5 (26.3)

  

Stage IV

3 (4.9)

1 (5.3)

  

histological_type (%)

Epithelioid Cell

10 (16.4)

3 (15.8)

0.888

Chisq Test

Spindle Cell

22 (36.1)

8 (42.1)

  

Spindle Cell|Epithelioid Cell

29 (47.5)

8 (42.1)

  

vital_status (%)

ALIVE

41 (67.2)

16 (84.2)

0.255

Chisq Test

DEAD

20 (32.8)

3 (15.8)

  

subtype (%)

subtype1

5 (8.2)

10 (52.6)

0.000

Chisq Test

subtype2

17 (27.9)

6 (31.6)

  

subtype3

21 (34.4)

1 (5.3)

  

subtype4

18 (29.5)

2 (10.5)

  

chromosome.3.status (%)

Disomy 3

22 (36.1)

16 (84.2)

0.001

Chisq Test

Monosomy 3

39 (63.9)

3 (15.8)

  

GEO

level

C1

C2

p

test

n

 

15

13

  

Age (%)

Age < 60

8 (53.3)

4 (30.8)

0.412

Fisher exact test

Age > =60

7 (46.7)

9 (69.2)

  

vital_status (%)

ALIVE

10 (66.7)

2 (15.4)

0.019

Fisher exact test

DEAD

5 (33.3)

11 (84.6)

  

Chromosome.3.status (%)

Disomy 3

11 (73.3)

3 (23.1)

0.023

Fisher exact test

Monosomy 3

4 (26.7)

10 (76.9)

  

Metastasis (%)

No

11 (73.3)

4 (30.8)

0.061

Fisher exact test

Yes

4 (26.7)

9 (69.2)

  
  1. M Metastasis, N Lymph Node, T Tumor size