Fig. 5
From: Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells
Dazl inhibited the formation of glioblastoma via inhibiting the stemness of glioblastoma cells. a Tumor growth was observed from GBM cells with Dazl alterations that were implanted subcutaneously in nude mice, n = 5; tumors were excised, photographed, and measured; b The tumor growth sizes were recorded every 6 days between Dazl WT and Dazl +/− GBM cell lines in xenograft tumor models, n = 5; data are shown as the mean ± SE. (***P < 0.001). c Q-RT-PCR analysis of stem cell gene expression in Dazl knockdown GBM cell lines. (*P < 0.05, **P < 0.01). d Western blot analysis of the relative protein levels of CD133, Oct4, Nanog, and Sox2 in Dazl+/− and WT GBM cells. Quantitative analysis of the relative protein levels of CD133, Oct4, Nanog, and Sox2 in GBM cells was carried out in triplicate. Data are shown as the mean ± SE. (*P < 0.05, **P < 0.01, ***P < 0.001)