Clinicopathological significance and prognosis of long noncoding RNA SNHG16 expression in human cancers: a meta-analysis

Table 2 Characteristics of included studies

Study (year)	Country	No. of patient	Cancer type	Sample	Method	Cut-off	Outcome	Extract method	NOS score
Cao (2018) [10]	China	46	Bladder cancer	Tissue	qRT-PCR	Mean	OS	Survival curves	8
Peng (2019) [11]	China	275	Bladder cancer	Tissue	qRT-PCR	Mean	OS	Data in paper	8
Zhu (2018) [12]	China	38	Cervical cancer	Tissue	qRT-PCR	–	OS	Survival curves	6
Li (2019) [13, 26]	China	56	Colorectal cancer	Tissue	qRT-PCR	Median	OS	Survival curves	8
Han (2018) [14]	China	128	Esophageal squamous cell carcinoma	Tissue	qRT-PCR	Median	OS	Data in paper	8
Wang (2019) [15, 22]	China	32	Gastric cancer	Tissue	qRT-PCR	Median	OS	Survival curves	8
Lu (2018) [16]	China	48	Glioma	Tissue	qRT-PCR	Median	OS PFS	Data in paper	7
Ye (2019) [17]	China	103	Hepatocellular carcinoma	Tissue	qRT-PCR	Mean	–	–	6
Guo (2019) [18]	China	61	Hepatocellular carcinoma	Tissue	ISH	–	OS	Data in paper	6
Lin (2019) [19]	China	88	Hepatocellular carcinoma	Tissue	qRT-PCR	Mean	OS	Survival curves	8
Han (2018) [14]	China	66	Non-small cell lung cancer	Tissue	qRT-PCR	Median	OS DFS	Data in paper	8
Liao (2019) [21]	China	96	Osteosarcoma	Tissue	qRT-PCR	Mean	OS	Survival curves	7
Wang (2019) [15, 22]	China	65	Osteosarcoma	Tissue	qRT-PCR	Median	OS	Survival curves	7
Yang (2018) [23]	China	103	Ovarian cancer	Tissue	qRT-PCR	–	OS	Survival curves	6
Liu (2019) [24]	China	46	Pancreatic cancer	Tissue	qRT-PCR	Median	OS	Survival curves	8
Wen (2019) [25]	China	48	Papillary thyroid cancer	Tissue	qRT-PCR	–	–	–	6

Abbreviations: OS overall survival, PFS progression free survival, DFS disease free survival, — not available, qRT-PCR quantitative reverse transcription polymerase chain reaction, ISH in situ hybridization, NOS Newcastle–Ottawa Scale

ISSN: 1471-2407