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Table 1 Patient Characteristics

From: A nomogram model to predict death rate among non-small cell lung cancer (NSCLC) patients with surgery in surveillance, epidemiology, and end results (SEER) database

Characteristics

All Patient

Training Cohort

Validation Cohort

(N = 44,880)

(N = 31,415)

(N = 13,465)

Number

%

Number

%

Number.

%

Diagnostic Age, years

 Mean

66.7

66.7

66.8

 Median

67

67

67

 Range

18–101

18–101

18–96

Gender

 Female

22,737

50.7

15,884

50.6

6853

50.9

 Male

22,143

49.3

15,531

49.4

6612

49.1

Ethnicity

 White

37,487

83.5

26,316

83.8

11,171

83

 Asian

3159

7

2160

6.9

999

7.4

 Black

3939

8.8

2742

8.7

1197

8.9

 Others/Unknown

295

0.7

197

0.6

98

0.7

Primary tumor location

 Left-sided

18,752

41.8

13,103

41.7

5649

42

 Right-sided

26,128

58.2

18,312

58.3

7816

58

Anatomic sites

 Upper

26,831

59.8

18,766

59.7

8065

59.9

 Middle

2152

4.8

1491

4.7

661

4.9

 Lower

14,237

31.7

9940

31.6

4297

31.9

 Bronchus/Others

1660

3.7

1218

3.9

442

3.3

Histologic subtype

 ADC

21,933

48.9

15,321

48.8

6612

49.1

 SCC

12,593

28.1

8871

28.2

3722

27.6

 BAC

4746

10.6

3292

10.5

1454

10.8

 ADSC

1279

2.8

909

2.9

370

2.7

 LCC

1279

2.8

900

2.9

379

2.8

 Others

1327

3

923

2.9

404

3

 Unspecified

1723

3.8

1199

3.8

524

3.9

Differentiation

 Well

6146

13.7

4292

13.7

1854

13.8

 Moderately

19,882

44.3

13,884

44.2

5998

44.5

 Poorly

17,783

39.6

12,485

39.7

5298

39.3

 Undifferentiated

1069

2.4

754

2.4

315

2.3

Clinical stage

 I

27,825

62

19,476

62

8349

62

 II

6715

15

4681

14.9

2034

15.1

 III

7982

17.8

5653

18

2329

17.3

 IV

2358

5.3

1605

5.1

753

5.6

Tumor size, cm

 Mean

3.4

3.4

3.4

 Median

2.8

2.8

2.8

 Range

1–20

1–20

1–20

Tumor extent

 Local

29,526

65.8

20,649

65.7

8877

65.9

 Regional

14,836

33.1

10,404

33.1

4432

32.9

 Distant

518

1.2

362

1.2

156

1.2

Lymph node stage

 N0

32,207

71.8

22,539

71.7

9668

71.8

 N1

6809

15.2

4733

15.1

2076

15.4

 N2

5700

12.7

4027

12.8

1673

12.4

 N3

164

0.4

116

0.4

48

0.4

Examined lymph node

 Mean

9.9

10

9.9

 Median

8

8

8

 Range

1–90

1–90

1–90

Positive lymph node

 Mean

0.8

0.8

0.8

 Median

0

0

0

 Range

0–41

0–41

0–39

Type of surgery

 Lobectomy

37,203

82.9

26,056

82.9

11,147

82.8

 Pneumonectomy

2830

6.3

1978

6.3

852

6.3

 Sub-lobar

4847

10.8

3381

10.8

1466

10.9

Chemotherapy

 None

31,835

70.9

22,214

70.7

9621

71.5

 Yes

13,045

29.1

9201

29.3

3844

28.5

Radiotherapy

 None

39,049

87

27,357

87.1

11,692

86.8

 Yes

5831

13

4058

12.9

1773

13.2

Lung cancer related death

12,958

28.9

9154

29.1

3804

28.3

Other cancer related death

510

1.1

352

1.1

158

1.2

Non-cancer related death

5357

11.9

3743

11.9

1614

12

Follow-up, months

 Mean

39.8

39.8

39.9

 Median

31

30

31

 Range

0–131

0–131

0–131

  1. ADC adenocarcinoma, ASDC adenosquamous carcinoma, BAC bronchoalveolar carcinoma, SCC squamous cell carcinoma, LCC large cell carcinoma