Table 3 Relationship between preexisting bood examination and irAE
irAE(−) | irAE(+) | p value | |
|---|---|---|---|
KL-6 | |||
n | 139 | 87 | 0.7 |
U/mL | 269 (182–458) | 289 (196–424) | |
ANA | |||
n | 131 | 84 | 0.87 |
positive rate(%) | 38.2 | 60.7 | |
TgAb | |||
n | 124 | 75 | 0.22 |
IU/mL | 0.9 (0.9–0.9) | 0.9 (0.9–5.6) | |
RF | |||
n | 115 | 80 | 0.08 |
positive rate(%) | 12.2 | 21.3 | |
anti AChR | |||
n | 118 | 67 | 0.53 |
positive rate(%) | 6.8 | 4.5 | |
TSH | |||
n | 150 | 104 | 0.79 |
μU/mL | 1.93 (0.95–3.09) | 1.81 (1.08–3.28) | |
FT3 | |||
n | 147 | 103 | 0.09 |
pg/mL | 2.33 ± 0.51 | 2.44 ± 0.48 | |
FT4 | |||
n | 149 | 104 | 0.34 |
ng/dL | 1.06 (0.96–1.22) | 1.06 (0.94–1.18) | |
ACTH | |||
n | 114 | 66 | 0.95 |
pg/mL | 27.7 (18.7–47.9) | 30.8 (16.7–45.3) | |
antiTPOA | |||
n | 111 | 60 | 0.53 |
U/L | 11.0 (9.0–12.0) | 11.0 (9.0–13.0) | |
AST | |||
n | 162 | 115 | 1.49 |
U/L | 21.0 (16.0–28.8) | 21.0 (17.0–28.0) | |
ALT | |||
n | 163 | 115 | 0.51 |
U/L | 14.0 (10.0–23.5) | 15.0 (11.0–23.5) | |
LDH | |||
n | 160 | 109 | 0.02 |
U/L | 213.5 (177.5–282.5) | 198.0 (168.0–236.0) | |
Alb | |||
n | 156 | 111 | 0.2 |
g/dL | 3.6 (3.1–3.9) | 3.7 (3.2–4.0) | |
CRP | |||
n | 162 | 110 | 0.91 |
mg/dL | 0.52 (0.11–2.27) | 0.46 (0.17–1.86) | |