Table 1 Summary of our patient therapies and its doses
Surgery | Bilateral mastectomy with axillary sentinel lymph node biopsy | pmT1b N0(sn) cM0 |
|---|---|---|
Adjuvant therapy | FEC100-TXT | 5-Fluorouracyl 500 mg/m2 Cyclophosphamide 500 mg/m2 Epirubicin 70 mg/m2 Docetaxel 100 mg/m2 |
1st line | Bevacizumab+TAX | Bevacizumab 15 mg/kg Paclitaxel 175 mg/m2 |
Radiotherapy | IMRT | 54 Gy simultaneous boost was given to the infra-axillary and axillary region and the operated area |
2nd line | CDDP+TXT | Cisplatin 75 mg/m2 Docetaxel 75 mg/m2 |
3rd line | XEL | Capecitabine 2500 mg/m2 |
4th line | PARP inhibitor | Olaparib 300 mg |
5th line | VNB | Vinorelbine 30 mg/m2 (only 2 cycle) |
6th line | Trastuzumab+TAX | Trastuzumab 4 mg/kg Paclitaxel 175 mg/m2 |
7th line | VNB/reinduction | Vinorelbine 30 mg/m2 |
8th line | CMF | 5-Fluorouracyl 600 mg/m2 Cyclophosphamide 600 mg/m2 Methotrexate 40 mg/m2 |