Fig. 2From: Sterile, abscess-like cerebral lesion during trastuzumab therapy after HER2 status switch in a triple negative breast cancer patient: a case report and literature reviewCore biopsy specimen of the tumor mass in the sternum region. a. Highly atypical, pleomorphic tumor cells are seen on the H&E section. b. HER2 immunohistochemistry c. FISH examination confirmed amplification of the HER-2 gene (red) in more than 30% of tumor cells, and chromosome 17 polysomy (green)Back to article page