Table 1 Clinical and pathological characteristics of the ccRCC patients from the Berazategui Hospital, Argentina. Reference values for Who/ISUP grade, age ranges, MVD index, metastasis, overall survival, local infiltration, tumor size (pT), expression of VEGF-A, HLA-G and ILT4, are provided. The expression levels of markers revealed by IHC were noted as follows: + weak staining; ++ moderate staining; +++ strong staining. Survival, reported as overall survival, is expressed in years considered at 1, 3 or 5 years post-surgery; MVD: Microvessel density index (central and peripheral zone); detection of metastasis: Yes (Y) or Not (N)
Patient | Who/ISUP | Age Range | Metastasis | Survival | VEGF-A | MVD | HLA-G | ILT4 | Local infiltration | pT |
|---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 70–79 | N | < 5 | + | 36 | ++ | +++ | No | T1 |
2 | 2 | 50–59 | N | > 5 | + | 29 | ++ | +++ | Capsule | T2 |
3 | 2 | 60–69 | Y | < 3 | + | 14 | ++ | +++ | Renal vein | T3 |
4 | 2 | 50–59 | N | > 5 | ++ | 24 | +++ | ++ | Capsule | T1 |
5 | 2 | 50–59 | N | > 5 | + | 38 | +++ | ++ | No | T1 |
6 | 2 | 60–69 | N | > 5 | ++ | 54 | +++ | +++ | Capsule | T1 |
7 | 2 | 60–69 | N | > 5 | +++ | 16 | ++ | +++ | Capsule | T1 |
8 | 2 | 50–59 | N | > 5 | ++ | 33 | +++ | +++ | Capsule | T2 |
9 | 2 | 50–59 | N | > 5 | + | 35 | +++ | +++ | Capsule | T1 |
10 | 2 | 50–59 | N | > 5 | ++ | 34 | ++ | +++ | No | T1 |
11 | 2 | 50–59 | N | > 5 | + | 33 | ++ | + | Capsule | T1 |
12 | 2 | 40–49 | N | > 5 | + | 42 | ++ | + | No | T1 |
13 | 2 | 50–59 | N | < 5 | ++ | 31 | +++ | +++ | Perirenal tissues | T3 |
14 | 3 | 70–79 | N | > 5 | +++ | 20 | +++ | +++ | Renal vein | T3 |
15 | 3 | 70–79 | Y | > 5 | ++ | 16 | ++ | +++ | Renal vein | T3 |
16 | 3 | 50–59 | N | > 5 | + | 19 | ++ | +++ | Perirenal tissues | T3 |
17 | 3 | 50–59 | N | < 3 | ++ | 27 | ++ | +++ | Perirenal tissues | T3 |
18 | 3 | 70–79 | N | > 5 | ++ | 26 | ++ | +++ | No | T1 |
19 | 3 | 50–59 | N | > 5 | + | 28 | ++ | + | No | T1 |
20 | 4 | 60–69 | Y | < 1 | ++ | 26 | + | +++ | Renal vein | T3 |