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Fig. 1 | BMC Cancer

Fig. 1

From: Farnesoid X receptor as marker of osteotropism of breast cancers through its role in the osteomimetism of tumor cells

Fig. 1

Panel a FXR expression in a case of breast cancer with bone metastases (score of 8) and a case with lung metastases (score of 2). The FXR score is higher in bone metastases (8) compared to lung metastases (2). Scale bars = 40 and 50 μm Panel b FXR expression in primary tumors in relation with first metastatic site. FXR was expressed in 98% of primary breast cancer with bone metastasis (median score 6) and in 68% (median score 4.5) with visceral metastasis. In grade 3 cancers, the predictive value of FXR was improved. The bone predictive value was 91% and the visceral one was 43%

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