Fig. 6

Matrix metalloprotease (MMP) 2, MMP9, and stromal cell-derived factor-1 (SDF-1) expression in the mouse model of peripheral blood hematopoietic stem cell mobilization. a MMP2, MMP9, and SDF-1 expression in the peripheral blood did not differ significantly among the groups (G-CSF only, n = 4; cyclophosphamide + G-CSF, n = 4; etoposide + G-CSF, n = 4). b, c, d In the bone marrow, the etoposide + G-CSF group showed a significant increase in MMP9 and decrease in SDF-1 expression, compared to the G-CSF only and cyclophosphamide + G-CSF groups (G-CSF only, n = 7; cyclophosphamide + G-CSF, n = 7; etoposide + G-CSF, n = 7). Note: ** p < 0.01 after Bonferroni correction; * p < 0.05 after Bonferroni correction. Note: Values are reported as the mean ± SEM. Abbreviations: G-CSF, granulocyte colony-stimulating factor; CY, cyclophosphamide; ETO, etoposide; n.s., not significant