Prediction of lymph node metastasis by tumor-infiltrating lymphocytes in T1 breast cancer

BMC Cancer

Table 5 Univariate and multivariate analysis with sentinel lymph node metastasis for cT1N0M0 breast cancer

Parameters	Univarite analysis			Multivarite analysis
Parameters	Odd ratio	95% CI	p value	Odd ratio	95% CI	p value
Age at operation (years old) ≤ 60 vs > 60	1.636	0.873–3.065	0.124
Tumor size (mm) ≤ 10.0 vs > 10.0	3.534	1.056–11.825	0.017	2.639	0.888–11.346	0.085
Estrogen receptor Negative vs Positive	1.249	0.528–2.955	0.606
Progesterone receptor Negative vs Positive	1.246	0.648–2.395	0.506
Hormone receptor Negative vs Positive	1.159	0.488–2.748	0.735
HER2 Negative vs Positive	1.205	0.392–3.700	0.749
Ki67 ≤ 14% vs > 14%	0.827	0.430–1.590	0.567
Lymphatic invasion ly0 vs ly1	2.792	1.476–5.282	0.002	2.522	1.280–4.973	0.008
Venous invasion v0 vs v1	2.794	0.823–9.481	0.124
Nuclear grade 1, 2 vs 3	1.215	0.475–3.105	0.689
TILs 0, 1 vs 2, 3	0.495	0.187–1.311	0.128
TILs 0 vs 1–3	0.117	0.049–0.277	< 0.001	0.137	0.055–0.335	< 0.001

CI confidence intervals, HER2 human epidermal growth factor receptor 2, TILs tumor- infiltrating lymphocytes

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