Totally informed of diagnosis versus uninformed of diagnosis | ||||
Patient: cancer patients | ||||
Intervention: totally informed of diagnosis | ||||
Comparison: uninformed of diagnosis | ||||
Outcomes | Sample Size (Number + Study Design) | Evidence Grade | Relative Effect (95% CI) | Prospective Absolute Effect (95%CI) |
General Quality of Life | 1593 (10 cohort studies) | Very Low1 ⊕ ○○○ | SMD 0.12 [− 0.09, 0.34] | SMD 0.12 SD higher (− 0.09 lower to 0.34 higher) |
Role Functioning | 1250 (9 cohort studies) | Low ⊕ ⊕ ○○ | MD 0.17 [−0.05, 0.39] | MD 0.17 higher (− 0.05 lower to 0.39 higher) |
Cognitive Activity | 1150 (8 cohort studies) | Very Low2 ⊕ ○○○ | SMD 0.61 [− 0.06, 1.28] | SMD 0.61 higher (− 0.06 lower to 1.28 higher) |
Vitality | 212 (3 cohort studies) | Very Low2 3 4 ⊕ ○○○ | SMD 2.22 [0.11, 4.33] | SMD 2.22 higher (0.11 lower to 4.33 higher) |
Emotional Function | 1793 (14 cohort studies) | Very Low 5 ⊕ ○○○ | SMD 0.13 [−0.20, 0.47] | SMD 0.13 higher (−0.20 lower to 0.47 higher) |
Social Function | 2045 (17 cohort studies) | Very Low 6 ⊕ ○○○ | SMD 0.58 [0.11, 1.05] | SMD 0.58 higher (0.11 lower to 1.05 higher) |
Physical Function | 1733 (13 cohort studies) | Low 7 ⊕ ⊕○○ | SMD 0.03 [−0.26, 0.32] | SMD 0.03 higher (− 0.26 lower to 0.32 higher) |
Nausea and Vomiting | 1250 (9 cohort studies) | Very Low 8 ⊕ ○○○ | SMD − 0.13 [− 0.46, 0.20] | SMD − 0.13 higher (− 0.46 lower to 0.20 higher) |
Pain | 1541 (13 cohort studies) | Very Low9 ⊕ ○○○ | SMD − 0.24 [− 0.61, 0.14] | SMD − 0.24 higher (− 0.61 lower to 0.14 higher) |
Dyspnea | 1250 (9 cohort studies) | Low ⊕ ⊕ ○○ | SMD − 0.01 [− 0.12, 0.10] | SMD − 0.01 higher (− 0.12 lower to 0.10 higher) |
Fatigue | 1250 (9 cohort studies) | Very Low10 ⊕ ○○○ | SMD 0.07 [− 0.23, 0.38] | SMD 0.07 higher (− 0.23 lower to 0.38 higher) |
Financial Difficulty | 1123 (9 cohort studies) | Very Low8 ⊕ ○○○ | SMD 0.14 (0.01 ~ 1.47) | SMD 0.14 higher (0.01 lower to 1.47 higher) |
Diarrhea | 1250 (9 cohort studies) | Very Low11 ⊕ ○○○ | SMD − 0.03 [− 0.21, 0.15] | SMD − 0.03 higher (− 0.21 lower to 0.15 higher) |
Constipation | 1250 (9 cohort studies) | Low ⊕ ⊕ ○○ | SMD 0.04 [− 0.12, 0.20] | SMD 0.04 higher (− 0.12 lower to 0.20 higher) |
Appetite Loss | 1250 (9 cohort studies) | Low ⊕ ⊕ ○○ | SMD 0.06 [− 0.05, 0.17] | SMD 0.06 higher (− 0.05 lower to 0.17 higher) |
Insomnia | 1250 (9 cohort studies) | Low ⊕ ⊕ ○○ | SMD 0.08 [− 0.05, 0.21] | SMD 0.06 higher (− 0.05 lower to 0.17 higher) |
Partly informed of diagnosis versus uninformed of diagnosis | ||||
Patient: cancer patients | ||||
Intervention: partly informed of diagnosis | ||||
Comparison: uninformed of diagnosis | ||||
General Quality of Life | 219 (3 cohort studies) | Very Low12 ⊕ ○○○ | SMD 0.23 [− 0.26, 0.72] | SMD 0.23 higher (− 0.26 lower to 0.72 higher) |
Pain | 217 (3 cohort studies) | Very Low3 4 ⊕ ○○○ | SMD − 0.15 [− 0.42, 0.13] | MD − 0.15 higher (− 0.42 lower to 0.13 higher) |
Physical Function | 286 (4 cohort studies) | Very Low3 4 ⊕ ○○○ | SMD 0.01 [− 0.22, 0.25] | SMD 0.01 higher (− 0.22 lower to 0.25 higher) |
Social Function | 296 (4 cohort studies) | Very Low3 4 ⊕ ○○○ | SMD 0.18 [− 0.15, 0.51] | SMD 0.18 higher (− 0.15 lower to 0.51 higher) |
Emotional Function | 296 (4 cohort studies) | Very Low3 4 ⊕ ○○○ | SMD − 1.24 [− 2.75, 0.26] | SMD − 1.24 higher (− 2.75 lower to 0.26 higher) |