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Table 1 Overall study characteristics

From: The impact on quality of life from informing diagnosis in patients with cancer: a systematic review and meta-analysis

Study origin Journal Country Financial support Length of follow-up Sample size (exposure VS non-exposure) Study design Interventions (exposure VS non-exposure) Cancer type Quality of life assessment scale Level of education (illiterate/primary/middle/college) (exposure VS non-exposure) Age /years* (exposure VS non-exposure)
Noritoshi 1998 [8] The Japan Society of Clinical Oncology Japan No report 1992.11 ~ 1997 23VS21 Cohort study Truth-Disclosed VS Truth-Concealed Gastrointestinal and Liver Cancer Functional Living Index Cancer (FLIC) Not report 59(54 ~ 63) VS 62(56 ~ 67)
H. Bozcuk 2001 [9] Support Care Cancer Turkey Not report Not report 56VS44 Cohort study Aware of diagnosis VS Not aware of diagnosis Gastrointestinal and Breast Cancer EORTC QLQ-C30 Not report Not report
Jianjun Zou 2006 [10] Chinese Journal of Oncology China Not report 2003.1 ~ 2004.2 69VS41 Cohort study Totally aware of the condition and partly aware of the condition VS Totally unaware of the condition Gastrointestinal, Breast, Lung, and other Cancer FACT-G 35/41/34/0 58 ± 12
Zhenjing Liu 2006 [11] Journal of Psychiatry China No report 2005.3 ~ 2005.9 60VS64 Cohort study Totally aware of the condition VS Totally unaware of the condition Unknown EORTC QLQ-C30 Not report 48 ± 12
Xiuling Wang 2006 [12] Journal of QiLu Nursing China Not report 1995.1–2006.1 40VS40 Cohort study Disclosed nursingVS Concealed nursing (disclose the truth to experiment group but conceal the truth to control group) Liver cancer SF-36 scale Not report Not report
Alexandra 2006 [13] Progress in Palliative Care Portugal Not report Not report 163VS75 Cohort study Aware of diagnosis VS Not aware of diagnosis Gastrointestinal, Breast, Lung, and other Cancer EORTC QLQ-C30 Not report 59.3 ± 12.4VS 70.0 ± 9.9
Liping Zhao 2007 [14] Journal of Nursing Science China Not report 2002.8 ~ 2003.1 54VS11 Cohort study Totally aware of the condition VS Totally unaware of the condition Liver cancer QLS-PLC 1/10/37/17 49.3 ± 13.6
Fang Ding 2008 [15] Chinese Nursing Research China Not report 2004 ~ 2006 85VS47 Cohort study Disclosed nursing VS Concealed nursing Unknown GQOLI −74 Not report 18 ~ 76
Lianxue Zheng 2009 [16] Journal of Shanxi Medical College for Continuing Education China Yes 2008.4 ~ 2008.7 83VS42 Cohort study Totally aware of the condition and partly aware of the condition VS Totally unaware of the condition Gastrointestinal cancer EORTC QLQ-C30 0/13/103/4 57.70(28 ~ 83)
Ruihong Kong 2009 [17] Today Nurse China Not report 2005.10 ~ 2007.12 115VS137 Cohort study Totally aware of the condition VS Totally unaware of the condition Unknown QLQ-CCC Not report Not report
Zhaoxia Li 2009 [18] Clinical Focus China Yes 2005 ~ 2008 87VS34 Cohort study Totally aware of the condition VS Totally unaware of the condition Lung cancer EORTC QLQ-C30 39/45/37/0 51.0 ± 14.1
Ali 2009 [19] BMC Cancer Iran No 2005.11 ~ 2006.4 68VS74 Cohort study Informed of the diagnosis VS uninformed of the diagnosis Gastrointestinal cancer EORTC QLQ-C30 23/28/9/8 VS 55/15/3/1 50.2 ± 13.9 VS 58.2 ± 13.4
Xue Xu 2011 [20] Master’ Thesis of Shandong University China Not report 2010.6 ~ 2011.4 83VS37 Cohort study Totally aware of the condition and partly aware of the condition VS Totally unaware of the condition Unknown EORTC QLQ-C30 Not report 55(26 ~ 78)
Xiaoping Fan 2011 [21] Journal of Palliative Medicine China Yes 2009.12 ~ 2010.07 86VS87 Cohort study Aware of diagnosis VS Not aware of diagnosis Gastrointestinal, Urogenital, Lung and other cancer EORTC QLQ-C30 5/26/37/18 VS 11/38/26/12 59.35 ± 11.60 VS 62.90 ± 12.20
Yuqian Sun 2012 [22] Chinese Journal of Behavioral Medicine and Brain Science China Yes 2010.12 ~ 2011.8 62VS68 Cohort study Totally aware of the condition VS Totally unaware of the condition Gastrointestinal cancer EORTC QLQ-C30 Not report 54.18 ± 15.51 VS 55.73 ± 14.96
Jie Luo 2012 [23] Cancer Research on Prevention and Treatment China No report 2007.6 ~ 2007.12 93VS22 Cohort study Totally informed of the diagnosis and partly informed the diagnosis VS totally uninformed of the diagnosis Lung cancer EORTC QLQ-C30 0/34/63/18 #
Lina Wang 2013 [24] Journal of Nurses Training China Not report 2012.1 ~ 2012.12 89VS98 Cohort study Totally aware of the condition VS Totally unaware of the condition Gastrointestinal cancer EORTC QLQ-C30 Not report 30.9 ± 11.3 VS 31.1 ± 11.0
Liping Fu 2013 [25] Chinese Journal of Gerontology China Not report 2007 ~ 2012 100VS100 Cohort study Totally aware of the condition VS Totally unaware of the condition Lung cancer EORTC QLQ-C30 Not report 73.5 ± 15.8
Zaili Feng 2014 [26] Anti-Tumor Pharmacy China Not report Not report 352VS68 Cohort study Informed of the diagnosis VS uninformed of the diagnosis Gastrointestinal, Breast, Lung, and other Cancer Jiacheng Li Foundation for Hospice Plan Quality Life Scale) Not report 48.0 ± 19.1 VS
49.7 ± 18.2
Yuanling Li 2014 [27] International Journal of Nursing China Not report 2011.12 ~ 2013.12 30VS30 Cohort study Disclosed nursing VS Concealed nursing Liver cancer SF-36 scale Not report 54.3 ± 19.4 VS 51.4 ± 17.9
Nobuhisa 2015 [28] American Journal of Hospice & Palliative Medicine Japan Not report 2004.4 ~ 2008.3 15VS10 Cohort study Informed VS uninformed Gastrointestinal, Liver and Breast Cancer STAS-J scale Not report 72.8 + 11.8
Bo Yang 2015 [29] Hainan Medical Journal China Not report 2012.9 ~ 2013.9 30VS63 Cohort study Totally aware of the condition VS Totally unaware of the condition Gastrointestinal, Breast, Lung, and other Cancer EORTC QLQ-C30 9/21/0/0 69.80 ± 5.11 VS 71.95 ± 5.45
Ruifen Zhang 2016 [30] Journal of Clinical Medical Literature China Not report 2005.2–2005.10 36VS36 Cohort study Disclosed nursing VS Concealed nursing Liver cancer SF-36 scale Not report 49.5 ± 0.8 VS 48.1 ± 1.9