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Table 4 Age- and multivariable-adjusted HRs for prostate cancer according to WC stratified by BMI

From: Does increased body mass index lead to elevated prostate cancer risk? It depends on waist circumference

 

HR (95% confidence interval)

BMI, kg/m2

WC, cm

Event

Person-years

Incidencea

Model 1b

Model 2c

<  18.5

WC < 85

462

318,733

144.95

Ref.

Ref.

85 ≤ WC < 90

4

4018

99.55

0.47 (0.18, 1.26)

0.48 (0.18, 1.27)

90 ≤ WC < 95

0

0

0

95 ≤ WC

0

0

0

18.5–22.9

WC < 85

6033

4,138,307

145.75

Ref.

Ref.

85 ≤ WC < 90

1086

594,059

182.81

1.16 (1.09, 1.24)

1.12 (1.05, 1.20)

90 ≤ WC < 95

196

94,269

207.91

1.14 (0.99, 1.31)

1.03 (0.89, 1.20)

95 ≤ WC

23

14,442

159.26

0.81 (0.54, 1.22)

0.72 (0.47, 1.11)

23.0–24.9

WC < 85

2874

2,046,401

140.44

Ref.

Ref.

85 ≤ WC < 90

2638

1,544,705

170.78

1.08 (1.03, 1.15)

1.09 (1.03, 1.15)

90 ≤ WC < 95

1065

542,265

196.39

1.04 (0.97, 1.12)

1.05 (0.98, 1.13)

95 ≤ WC

198

85,297

232.13

0.99 (0.86, 1.15)

0.98 (0.85, 1.14)

25.0–29.9

WC < 85

904

703,159

128.56

Ref.

Ref.

85 ≤ WC < 90

2150

1,601,586

134.24

1.01 (0.93, 1.09)

1.01 (0.93, 1.09)

90 ≤ WC < 95

2665

1,714,191

155.27

1.04 (0.96, 1.12)

1.03 (0.95, 1.11)

95 ≤ WC

1841

1,020,521

180.39

1.03 (0.95, 1.11)

1.01 (0.93, 1.09)

≥ 30

WC < 85

0

0

0

85 ≤ WC < 90

0

0

0

90 ≤ WC < 95

63

47,291

133.22

Ref.

Ref.

95 ≤ WC

382

272,054

140.41

0.93 (0.71, 1.21)

0.92 (0.69, 1.21)

  1. BMI body mass index, WC waist circumference, HR hazard ratio
  2. aAll rates are expressed as number per 100,000 person-years
  3. bAdjusted for age
  4. cAdjusted for age, diabetes, hypertension, dyslipidemia, smoking status, and alcohol consumption