Fig. 1

Differentially methylated CGs and respective gene-related pathways deregulated in PCa compared to the controls. A total of 223 statistically significant CGs which had 10% methylation difference in T cell DNA between Ctrl and PCa (p < 0.05). a Heatmap of the 223 CGs shown for each sample. The scale bar shows methylation levels where highest is 100% and lowest is 0% of that CpG; Blue; hypomethylation; Red; hypermethylation. b Differentially methylated genes nearby 105 CGs showed various pathways involved in immune system and immuno-surveillance system. These pathways were obtained by conducting an overrepresentation analysis of the genes nearby 105 CGs utilizing ConsensusPath DB. The pathways have been plotted against -log10 of the p value