Fig. 2
From: Immune-related genes in tumor-specific CD4+ and CD8+ T cells in colon cancer
Gene expression profiles for colon cancer tissue samples. Volcano plot showing the expression profiles of genes in groups with high or low stromal scores (a) and with high or low immune scores (b). The red and green dots in the volcano plot represent up-regulated and down-regulated genes, respectively. Venn diagram (c) showing overlapping differentially expressed genes in analyses of genes related to stromal scores and immune scores. The GDC TCGA Colon Cancer (COAD) dataset (version 07-19-2019) was downloaded from TCGA (https://xenabrowser.net/). For the analysis of the infiltrating stromal and immune cells in tumor tissues, Estimation of STromal and Immune cells in MAlignant Tumours using Expression data (ESTIMATE, version 1.0.13) implemented in R was used