Fig. 6
OTUD3 inhibits cell proliferation. a MCF7 and DU4475 cells transfected with OTUD3 and OTUD3C76A were seeded in 96-well plates. Cell proliferation was measured by MTS assay at the indicated time. Data were analyzed using two-way ANOVA. Data are shown as the mean ± SEM of three independent experiments. b OTUD3 was knocked down by shRNA, and the OTUD3 and OTUD3C76A levels were restored without shRNA interference for proliferation detection. The data are presented as the mean ± standard deviation of three independent experiments. *p < 0.05, **p < 0.01