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Fig. 5 | BMC Cancer

Fig. 5

From: Sophoridine exerts tumor-suppressive activities via promoting ESRRG-mediated β-catenin degradation in gastric cancer

Fig. 5

SOP depends on ESRRG to perform tumor-suppressive activities in gastric cancer cells. AGS cells transfected with siRNA non-target control (siNC) or ESRRG siRNA were treated with or without 3 μM SOP for 24 h. a EDU assay was used to evaluate cell viability; b the clones were visualized by crystal violet staining. c Statistical analysis of colony numbers in AGS cells. d Apoptotic AGS cells were determined by flowcytometry. e migration and invasion of AGS cells were determined by transwell assay. The results are representatives of at least 3 independent experiments. Data were presented as mean ± SD. **P < 0.01; ***P < 0.0001; NS, no significant difference. Abbreviation: SOP, Sophoridine

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