Skip to main content
Fig. 1 | BMC Cancer

Fig. 1

From: Sophoridine exerts tumor-suppressive activities via promoting ESRRG-mediated β-catenin degradation in gastric cancer

Fig. 1

SOP inhibits proliferation and colony formulation in gastric cancer cells. a Human gastric epithelial cells (GES-1) and gastric cancer cell lines AGS, SGC7901 were treated with SOP in indicated concentrations for 24 h. Cytotoxicity was assessed with a CCK-8 assay, and IC50 values were calculated by Graphpad software. b AGS and SGC7901 cells were treated with or without 3 μM SOP for 24 h and then EdU assay was used to evaluate cell viability. c Statistical analysis of the EdU-positive cell ratio in AGS and SGC7901 cells. d AGS and SGC7901 cells were treated with 3 μM SOP and the clones were visualized by crystal violet staining. e Statistical analysis of colony numbers in AGS and SGC7901 cells. The results are representatives of at least 3 independent experiments. Data were presented as mean ± SD. ***P < 0.0001. Abbreviation: SOP, Sophoridine

Back to article page