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Table 3 The results of linear dose-response analysis between body mass index (BMI) and lymph node metastasis of breast cancer

From: Body mass index increases the lymph node metastasis risk of breast cancer: a dose-response meta-analysis with 52904 subjects from 20 cohort studies

Variables Number of cases Test of heterogeneity Model Regression model test RR (95%CI)
All 52904 χ 2=30.34, P=0.048 RE χ 2=29.30, P<0.001 1.0089 (1.0057, 1.0122)
Area
 Asia 8854 χ 2=4.71, P=0.095 FE χ 2=11.13, P=0.001 1.0099 (1.0041, 1.0157)
 Europe 28979 χ 2=13.70, P=0.057 FE χ 2=36.31, P<0.001 1.0085 (1.0057, 1.0113)
 America 8701 χ 2=5.16, P=0.641 FE χ 2=6.01, P=0.014 1.0061 (1.0012, 1.0110)
Menopausal
 Pre 8994 χ 2=10.53, P=0.032 RE χ 2=5.61, P=0.018 1.0144 (1.0025, 1.0264)
 Post 12456 χ 2=2.57, P=0.766 FE χ 2=23.48, P<0.001 1.0145 (1.0086, 1.0204)
Study period      
 ≤ 5y 4901 χ 2=3.66, P=0.600 FE χ 2=19.94, P<0.001 1.0222 (1.0124, 1.0321)
 > 5y 48003 χ 2=16.61, P=0.218 FE χ 2=40.88, P<0.001 1.0061 (1.0042, 1.0080)
  1. RE Random effect, FE Fixed effect