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Table 2 Subgroup analyses showing difference between studies included in the meta-analysis (highest versus lowest BMI)

From: Body mass index increases the lymph node metastasis risk of breast cancer: a dose-response meta-analysis with 52904 subjects from 20 cohort studies

Variables Number of studies Number of cases Pooled RR (95%CI) Test of heterogeneity Publication bias
I2(%) P value Begg's P value Egger's P value
All 20 30938 1.10 (1.06, 1.15) 43.0 0.022 0.538 0.003
Area
 Asia 3 2968 1.18 (1.08, 1.30) 0.0 0.555 1.000 0.339
 Europe 8 19791 1.08 (1.05, 1.12) 44.6 0.082 0.266 0.116
 America 8 3847 1.13 (1.04, 1.23) 47.4 0.065 0.902 0.079
Menopausal
 Pre 5 4291 1.12 (1.04, 1.20) 31.6 0.211 0.806 0.489
 Post 6 4479 1.28 (1.14, 1.44) 0.0 0.865 0.452 0.656
Study period
 ≤ 5y 6 2250 1.31 (1.14, 1.50) 0.0 0.709 0.707 0.860
 > 5y 14 28688 1.07 (1.05, 1.10) 26.8 0.167 0.743 0.051
Study population
 TNBC 2 429 1.15 (0.88, 1.49) 0.0 0.789 1.000 ---
 Non-TNBC 18 30539 1.08 (1.06, 1.11) 48.2 0.012 0.363 0.003
  1. TNBC Triple-negative breast cancer