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Table 3 Characteristics of patients according to PLR

From: Neutrophil-lymphocyte ratio associated with poor prognosis in oral cancer: a retrospective study

Variables

PLR

P value

Low, n (%)

High, n (%)

Number of patients

240 (55.4)

193 (44.6)

 

Sex

 Male

156 (65.0)

90 (46.6)

<  0.001 *

 Female

84 (35.0)

103 (53.4)

 

Age

 Range (Years)

27–98

22–92

 

 Mean ± SD

66.1 ± 12.7

66.6 ± 14.4

0.253 **

  ≥ 64

100 (41.7)

73 (37.8)

0.431 *

  ≤ 65

140 (58.3)

120 (62.2)

 

Smoking history

 No

115 (47.9)

104 (53.9)

0.002 *

 Yes

51 (21.3)

18 (9.3)

 

 Unknown

74 (30.8)

71 (36.8)

 

Alcohol consumption

 No

84 (35.0)

68 (35.2)

0.473 *

 Yes

78 (32.5)

53 (27.5)

 

 Unknown

78 (32.5)

72 (37.3)

 

Performance status

 0

135 (56.3)

92 (47.7)

0.081 *

  ≥ 1

103 (38.8)

99 (41.3)

 

 Unknown

2 (0.8)

2 (1.0)

 

Subsite

 Tongue

126 (52.5)

85 (44.0)

0.083 *

 Other

114 (47.5)

108 (56.0)

 

T classification

 1, 2

176 (73.3)

125 (64.8)

0.059 *

 3, 4a/b

64 (26.7)

68 (35.2)

 

N classification

 0

168 (70.0)

128 (66.3)

0.467 *

 Others

72 (30.0)

65 (33.7)

 

Pathological status

 Pathological extranodal extension

  ENE -

49 (57.6)

40 (54.8)

0.750 *

  ENE +

36 (42.4)

33 (45.2)

 

 Number of pathological lymph node metastases

  0, 1

94 (63.9)

79 (63.2)

0.900 *

   ≥ 2

53 (36.1)

46 (36.8)

 

 Surgical margins

  Negative

184 (76.7)

143 (74.1)

0.421 *

  Involved margins

51 (21.3)

48 (24.9)

 

  Unknown

5 (2.1)

2 (1.0)

 

 Histological differentiation

  Well differentiated

142 (59.2)

119 (61.7)

0.691 *

  Moderately or poorly differentiated

95 (39.6)

73 (37.8)

 

  Unknown

3 (1.3)

1 (0.5)

 
  1. ENE Extranodal extension; PLR Platelet-to-lymphocyte ratio
  2. *: Fisher’s exact test **: Mann–Whitney U test