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Table 3 Characteristics of patients according to PLR

From: Neutrophil-lymphocyte ratio associated with poor prognosis in oral cancer: a retrospective study

VariablesPLRP value
Low, n (%)High, n (%)
Number of patients240 (55.4)193 (44.6) 
Sex
 Male156 (65.0)90 (46.6)<  0.001 *
 Female84 (35.0)103 (53.4) 
Age
 Range (Years)27–9822–92 
 Mean ± SD66.1 ± 12.766.6 ± 14.40.253 **
  ≥ 64100 (41.7)73 (37.8)0.431 *
  ≤ 65140 (58.3)120 (62.2) 
Smoking history
 No115 (47.9)104 (53.9)0.002 *
 Yes51 (21.3)18 (9.3) 
 Unknown74 (30.8)71 (36.8) 
Alcohol consumption
 No84 (35.0)68 (35.2)0.473 *
 Yes78 (32.5)53 (27.5) 
 Unknown78 (32.5)72 (37.3) 
Performance status
 0135 (56.3)92 (47.7)0.081 *
  ≥ 1103 (38.8)99 (41.3) 
 Unknown2 (0.8)2 (1.0) 
Subsite
 Tongue126 (52.5)85 (44.0)0.083 *
 Other114 (47.5)108 (56.0) 
T classification
 1, 2176 (73.3)125 (64.8)0.059 *
 3, 4a/b64 (26.7)68 (35.2) 
N classification
 0168 (70.0)128 (66.3)0.467 *
 Others72 (30.0)65 (33.7) 
Pathological status
 Pathological extranodal extension
  ENE -49 (57.6)40 (54.8)0.750 *
  ENE +36 (42.4)33 (45.2) 
 Number of pathological lymph node metastases
  0, 194 (63.9)79 (63.2)0.900 *
   ≥ 253 (36.1)46 (36.8) 
 Surgical margins
  Negative184 (76.7)143 (74.1)0.421 *
  Involved margins51 (21.3)48 (24.9) 
  Unknown5 (2.1)2 (1.0) 
 Histological differentiation
  Well differentiated142 (59.2)119 (61.7)0.691 *
  Moderately or poorly differentiated95 (39.6)73 (37.8) 
  Unknown3 (1.3)1 (0.5) 
  1. ENE Extranodal extension; PLR Platelet-to-lymphocyte ratio
  2. *: Fisher’s exact test **: Mann–Whitney U test