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Table 1 Characteristics of patients according to NLR

From: Neutrophil-lymphocyte ratio associated with poor prognosis in oral cancer: a retrospective study

VariablesNLRP value
Low, n (%)High, n (%)
Number of patients233 (53.8)200 (46.2) 
Sex
 Male142 (60.9)104 (52.0)0.065 *
 Female91 (39.1)96 (48.0) 
Age
 Range (Years)27–9822–92 
 Mean ± SD65.7 ± 13.067.0 ± 14.00.170 **
  ≥ 6495 (40.8)78 (39.0)0.768 *
  ≤ 65138 (59.2)122 (61.0) 
Smoking history
 No112 (48.1)107 (53.5)0.179 *
 Yes47 (20.2)22 (11.0) 
Unknown74 (31.8)71 (35.5) 
Alcohol consumption
 No81 (34.8)71 (35.5)0.472 *
 Yes76 (32.6)55 (27.5) 
 Unknown76 (32.6)74 (37.0) 
Performance status
 0131 (56.2)96 (48.0)0.121 *
  ≥ 1101 (43.4)101 (50.5) 
 unknown1 (0.4)3 (1.5) 
Subsite
 Tongue116 (49.8)95 (47.5)0.700 *
 Other117 (50.2)105 (52.5) 
T classification
 1, 2167 (71.7)134 (67.0)0.297 *
 3, 4a/b66 (28.3)66 (33.0) 
N classification
 0168 (72.1)128 (64.0)0.078 *
 Others65 (27.9)72 (36.0) 
Pathological status
 Pathological extranodal extensions
  ENE -44 (57.9)45 (54.9)0.750 *
  ENE +32 (42.1)37 (45.1) 
 Number of pathological lymph node metastases
 0, 1101 (69.2)72 (57.1)0.044 *
  ≥ 245 (30.8)54 (42.9) 
Surgical margins
 Negative180 (77.3)147 (73.5)0.358 *
 Involved margins49 (21.0)50 (25.0) 
 Unknown4 (1.7)3 (1.5) 
Histological differentiation
 Well differentiated135 (57.9)126 (63.0)0.372 *
 Moderately or poorly differentiated95 (40.8)73 (36.5) 
 Unknown3 (1.3)1 (0.5) 
  1. ENE Extranodal extension; NLR Neutrophil-lymphocyte ratio
  2. *: Fisher’s exact test **: Mann–Whitney U test