Skip to main content

Table 2 The univariate and multivariate Cox analysis of overall survival in the unmatched cohort

From: Impact of liver fibrosis score on prognosis after common therapies for intrahepatic cholangiocarcinoma: a propensity score matching analysis

 

Univariate analysis

Multivariate analysis

Characteristics

HR

95%CI

P value

HR

95%CI

P value

Sex, Male vs. Female

1.239

1.047–1.466

0.013

1.386

1.157–1.661

< 0.001

Age years, ≤60 vs. > 60

0.838

0.701–1.003

0.054

   

Marital status

 Married

ref

     

 Single

1.211

1.017–1.441

0.032

   

 Unknown

1.175

0.788–1.752

0.430

   

Year of diagnosis, 2010–2015 vs. Elarly

0.838

0.702–1.001

0.052

   

Ethnicity

 Black

ref

     

 Other

0.760

0.52–1.112

0.157

   

 White

0.917

0.66–1.273

0.605

   

 AFP, ng/ml

ref

     

  > 15 vs. ≤15

1.140

0.906–1.434

0.263

   

 Unknown vs. ≤15

1.134

0.925–1.391

0.225

   

 Fibrosis score, 5–6 vs. 0–4

1.371

1.154–1.628

< 0.001

1.282

1.067–1.541

0.008

 Number of tumors, Multi vs. Single

1.385

1.138–1.685

0.001

1.548

1.258–1.904

< 0.001

Tumor size, cm

 3 cm

ref

     

  ≤ 3 cm

0.475

0.364–0.62

< 0.001

0.517

0.39–0.684

< 0.001

 Unknown

2.029

1.647–2.499

< 0.001

   

 Lymph nodes metastasis, No

ref

     

 Yes

1.738

1.434–2.107

< 0.001

   

 Unknown

2.240

1.427–3.516

< 0.001

   

 Distance metastasis, No

ref

     

 Yes

3.605

2.976–4.368

< 0.001

2.376

1.112–5.078

0.026

 Unknown

5.010

2.48–10.118

< 0.001

2.792

1.035–7.533

0.043

 6th AJCC TNM stage

  I

ref

     

  II

1.471

1.065–2.032

0.019

1.934

1.39–2.692

< 0.001

  III

2.291

1.806–2.907

< 0.001

2.495

1.776–3.506

< 0.001

  IV

5.402

4.245–6.875

< 0.001

1.750

0.695–4.403

0.235

  Unstaged

3.974

2.811–5.618

< 0.001

4.144

2.481–6.92

< 0.001

Pathological grade

 I

ref

     

 II

0.940

0.64–1.38

0.751

0.669

0.452–0.991

0.045

 III

1.545

1.043–2.288

0.030

0.988

0.659–1.481

0.954

 IV

1.206

0.424–3.4

0.731

0.718

0.247–2.082

0.542

 Unstaged

2.026

1.391–2.951

< 0.001

1.235

0.831–1.834

0.297

Surgery record, Yes vs. No

0.221

0.184–0.266

< 0.001

0.305

0.242–0.383

< 0.001

Radiation record, Yes vs. No

0.874

0.692–1.102

0.255

   

Chemotherapy record, Yes vs. No

0.830

0.702–0.983

0.031

0.490

0.407–0.589

< 0.001

  1. Abbreviation: HR Hazard ratio, CI confidence interval, AFP serum alpha fetoprotein, AJCC American Joint Committee on cancer
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us