Table 3 The initial levels of serum bone bimarkers in lung cancer patients who developed bone metastasis and the others who remained free of bone metastasis during follow-up
Serum bone marker at initial level | |||
|---|---|---|---|
Marker | Yes (n = 16) | No (n = 28) | P value |
BME cytokine | |||
CaN (ng/mL) | 1263.54 (1713.01) | 1287.27 (1418.43) | 0.625 |
OPG (ng/mL) | 1784.69 (2319.0) | 1638.18 (1789.94) | 0.105 |
PTHrP (pg/mL) | 401.12 (476.32) | 380.38 (431.93) | 0.28 |
IL-6 (pg/mL) | 23.73 (30.01) | 23.29 (45.19) | 0.136 |
Bone turnover marker | |||
tP1NP (μg/L) | 80.83 (101.60) | 71.06 (81.62) | 0.11 |
β-CTx (ng/L) | 610.0 (894.06) | 489.58 (624.24) | 0.081 |