Skip to main content

Table 2 Multivariate analysis of relapse-related factors among high-risk t(8;21) AML

From: Allogeneic hematopoietic stem cell transplantation can improve the prognosis of high-risk pediatric t(8;21) acute myeloid leukemia in first remission based on MRD-guided treatment

Covariate

HR

95% CI

P

EI (with vs. without)

4.750

1.537–14.678

0.007

Treatment (HSCT vs. chemotherapy)

0.238

0.064–0.883

0.032

Age (≥10 years vs. < 10 years)a

0.451

0.143–1.423

0.174

WBC (≥20 × 109 /L vs. < 20 × 109)a

NS

NS

NS

c-KIT mutations (with vs. without)

NS

NS

NS

CD56 (positive vs. negative)

NS

NS

NS

CR after first inducement (yes vs. no)

NS

NS

NS

  1. Abbreviations: CI confidence interval, CR complete remission, EI extramedullary infiltration, HR hazard ratio, HSCT hematopoietic stem cell transplantation, WBC white blood cell
  2. aCutoff based on median values