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Table 1 Characteristics of enrolled patients

From: Allogeneic hematopoietic stem cell transplantation can improve the prognosis of high-risk pediatric t(8;21) acute myeloid leukemia in first remission based on MRD-guided treatment

Characteristics

High-risk

Low-risk

High-risk chemotherapy

High-risk HSCT

P

Total

Age (years)

9.5 ± 3.3

10.4 ± 4.3

0.036

8.7 ± 3.6

Gender (male/female)

14/14

18/9

0.072

38/32

WBC (109)

25.6 ± 19.1

22.7 ± 26.4

0.697

16.8 ± 15.8

EI (%)

25

18.5

0.561

21.4

c-KIT mutation (%)

42.8

33.3

0.094

27.1

MRD after induction (%)

4.2 ± 9.7

3.1 ± 5.1

0.269

1.9 ± 1.2

MRD after the first consolidation (%)

1.4 ± 2.9

2.1 ± 3.4

0.226

0.08 ± 0.14

MRD after the second consolidation (%)

0.54 ± 1.0

0.9 ± 1.0

0.365

0.01 ± 0.01

  1. Abbreviations: EI extramedullary infiltration, HSCT hematopoietic stem cell transplantation, MRD minimal residual disease, WBC white blood cell