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Table 3 Self-reported chemotherapy-induced toxicities 1 week after chemotherapy comparing cycles of mSTF (n = 56) with cycles of NC (n = 62)

From: Impact of modified short-term fasting and its combination with a fasting supportive diet during chemotherapy on the incidence and severity of chemotherapy-induced toxicities in cancer patients - a controlled cross-over pilot study

 NCmSTFPE ± SD*95% CIP-Value
Reduced Appetite4.51 ± 5.012.75 ± 4.75− 1.01 ± 0.71−2.43 – 0.420.164
Hunger5.36 ± 5.484.98 ± 5.23− 0.14 ± 0.60−1.35 – 1.060.813
Nausea3.72 ± 4.344.24 ± 4.91− 0.13 ± 0.57−1.26 – 0.990.814
Vomiting0.21 ± 0.840.45 ± 1.140.32 ± 0.19− 0.07 – 0.700.106
Stomach pains1.66 ± 3.252.25 ± 3.690.79 ± 0.63− 0.47 – 2.040.215
Diarrhea1.00 ± 2.880.78 ± 2.34− 0.41 ± 0.58−1.57 – 0.760.489
Obstipation3.17 ± 4.423.06 ± 3.83− 0.73 ± 0.84− 2.41 – 0.940.385
Fever0.11 ± 0.510.14 ± 0.980.13 ± 0.18− 0.23 – 0.480.480
Headaches2.74 ± 4.301.18 ± 2.06− 1.80 ± 0.55−2.89 – (− 0.71)0.002
Insomnia5.21 ± 5.354.18 ± 4.97− 1.18 ± 0.77−2.73 – 0.360.130
Fatigue7.96 ± 5.526.63 ± 5.66− 1.45 ± 0.85−3.15 – 0.260.094
Dizziness2.23 ± 9.192.84 ± 4.15− 0.13 ± 0.59−1.31 – 1.050.832
Weakness7.11 ± 5.405.78 ± 5.26−1.99 ± 0.87−3.72 – (− 0.26)0.024
Exhaustion6.74 ± 5.466.20 ± 5.67−1.23 ± 0.85− 2.92 – 0.460.152
Total toxicities56.36 ± 32,1447.52 ± 33.21−10.36 ± 4.44−19.22 – (− 1.50)0.023
  1. Values are shown as mean ± SD. Due to missing data, we included data of 53 cycles of NC and 51 cycles of mSTF in this analysis. * PE ± SD represents the difference for each toxicity score points between cycles of NC and those of mSTF. Per day, patients awarded each toxicity with 0 (none) to 3 (severe) points. Consequently, each toxicity received 0–21 points. The scores of all toxicities in the following 7 days after chemotherapy are summarised in total toxicities (0–294 points)