Fig. 1
From: Metabolic profile of leukemia cells influences treatment efficacy of L-asparaginase
Basal metabolic state of leukemia cell lines. a Hierarchical cluster analysis of leukemia cell lines based on the parameters calculated from their glycolytic function. b Hierarchical cluster analysis of leukemia cell lines based on the parameters calculated from their mitochondrial function. Type of leukemia and IC50 ASNase [IU/ml] are indicated for each cell line. c Oxygen consumption rate (OCR) level against the extracellular acidification rate (ECAR) level of the leukemia cell lines after glucose injection in the measurement of Glycolysis Stress Test. The type of leukemia is indicated in (a) and (b). All the Seahorse measurements were done at least in biological triplicates and 5 technical replicates and are presented as a mean ± SD