Clinicopathological parameter | Studies(n) | OR(95% CI) | p-value | Heterogeneity | ||
---|---|---|---|---|---|---|
I2 (%) | PQ | Model | ||||
Gender (male vs. female) | 8 | 1.00(0.78–1.29) | 0.990 | 0.0 | 0.699 | Fixed |
Recurrence (+ vs. -) | 3 | 2.30(1.34–3.95) | 0.002 | 14.2 | 0.312 | Fixed |
Tumor depth (T3–4 vs. T1–2) | 4 | 2.72(1.73–4.30) | < 0.0001 | 0.0 | 0.488 | Fixed |
Lymph node metastasis (+ vs. -) | 10 | 2.69(1.71–4.24) | < 0.0001 | 56.4 | 0.014 | Random |
Distant metastasis (+ vs. -) | 3 | 10.35(1.01–106.24) | 0.049 | 90.0 | < 0.0001 | Random |
TNM stage (III-IV vs. I-II) | 7 | 2.75(2.04–3.71) | < 0.0001 | 32.7 | 0.179 | Fixed |
Poorly/undifferentiated vs. well/moderately | 6 | 1.78(1.03–3.09) | < 0.0001 | 62.8 | 0.020 | Random |
Vascular invasion (+ vs. -) | 3 | 2.43 (0.85–6.94) | 0.097 | 71.7 | 0.029 | Random |