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Fig. 2 | BMC Cancer

Fig. 2

From: Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging (HIPPORAD) – a phase II prospective randomized multicenter trial (NOA-14, ARO 2015–3, DKTK-ROG)

Fig. 2

Example of dose distribution and dose-volume histogram of a HA-WBRT+SIB plan in a patient with 7 brain metastases. HAR = hippocampus avoidance region; PTVmet = planning target volume for metastasis (gross tumor volume + 1 mm); PTV Whole brain (whole brain + 5 mm – HAR– PTVmets). Mean dose in the hippocampi under 10 Gy, mean dose for whole brain and metastases 30 and 51 Gy respectively

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BMC Cancer

ISSN: 1471-2407

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