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Table 4 Multivariate analyses of prognostic factors for CSS of stage III gastric cancer

From: Clinical significance of prognostic inflammation-based and/or nutritional markers in patients with stage III gastric cancer

Variables

Analysis with CAR

Analysis with PLR

HR (95% CI)

p value

HR (95% CI)

p value

Location

 Upper/Middle/Lower

1

 

1

 

 Whole

1.099 (0865–1.395)

0.439

1.083 (0.852–1.376)

0.516

Operative procedure

 Distal gastrectomy

1

 

1

 

 Total gastrectomy

1.723 (1.110–2.676)

0.015

1.705 (1.100–2.643)

0.017

TNM sub-stage

 IIIA

1

0.002

1

0.001

 IIIB

2.019 (1.187–3.435)

0.010

2.015 (1.184–3.432)

0.010

 IIIC

2.617 (1.534–4.467)

< 0.001

2.799 (1.635–4.792)

< 0.001

Tumor size (mm)

  ≤ 60

1

 

1

 

  > 60

0.978 (0.630–1.519)

0.921

0.946 (0.605–1.481)

0.809

CAR

 Low (≤0.47)

1

   

 High (> 0.47)

2.771 (1.398–5.493)

0.004

  

PLR

 Low (≤172)

  

1

 

 High (> 172)

  

1.552 (1.029–2.341)

0.036

  1. TNM tumor-node-metastasis, CAR C-reactive protein/Albumin ratio, PLR platelet to lymphocyte ratio