Variables | CAR | p value | PLR | p value | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Low | High | Low | High | |||||||
n | % | n | % | n | % | n | % | |||
Age (years) | ||||||||||
≤ 68 | 115 | 54.5 | 2 | 14.3 | 74 | 52.5 | 43 | 51.2 | ||
> 68 | 96 | 45.5 | 12 | 85.7 | 0.004 | 67 | 47.5 | 41 | 48.8 | 0.851 |
Sex | ||||||||||
Male | 136 | 64.5 | 11 | 78.6 | 99 | 70.2 | 48 | 57.1 | ||
Female | 75 | 35.5 | 3 | 21.4 | 0.389 | 42 | 29.8 | 36 | 42.9 | 0.046 |
BMI (kg/m2) | ||||||||||
Low (≤21.9) | 105 | 49.8 | 9 | 64.3 | 61 | 43.3 | 53 | 63.1 | ||
High (> 21.9) | 106 | 50.2 | 5 | 35.7 | 0.293 | 80 | 56.7 | 31 | 36.9 | 0.004 |
Performance status | ||||||||||
0 | 161 | 76.3 | 6 | 42.9 | 107 | 75.9 | 60 | 71.4 | ||
1–3 | 50 | 23.7 | 8 | 57.1 | 0.006 | 34 | 24.1 | 24 | 28.6 | 0.460 |
Location | ||||||||||
U/M/L | 197 | 93.4 | 12 | 85.7 | 132 | 93.6 | 77 | 91.7 | ||
Whole | 14 | 6.6 | 2 | 14.3 | 0.261 | 9 | 6.4 | 7 | 8.3 | 0.582 |
Macroscopic type | ||||||||||
Type 0/1/2 | 59 | 28.0 | 2 | 14.3 | 41 | 29.1 | 20 | 23.8 | ||
Type 3/4/5 | 152 | 72.0 | 12 | 85.7 | 0.361 | 100 | 70.9 | 64 | 76.2 | 0.390 |
Operative procedure | ||||||||||
Distal gastrectomy | 110 | 52.1 | 7 | 50.0 | 72 | 51.1 | 45 | 53.6 | ||
Total gastrectomy | 101 | 47.9 | 7 | 50.0 | 0.877 | 69 | 48.9 | 39 | 46.4 | 0.716 |
Lymph node dissection | ||||||||||
D1 | 30 | 14.2 | 2 | 14.3 | 19 | 13.5 | 13 | 15.5 | ||
D2 | 181 | 85.8 | 12 | 85.7 | 1.000 | 122 | 86.5 | 71 | 84.5 | 0.678 |
Histology | ||||||||||
Differentiated | 91 | 43.1 | 6 | 42.9 | 58 | 41.1 | 39 | 46.4 | ||
Undifferentiated | 120 | 56.9 | 8 | 57.1 | 0.984 | 83 | 58.9 | 45 | 53.6 | 0.438 |
Lymphatic invasion | ||||||||||
Absent | 18 | 8.5 | 1 | 7.1 | 13 | 9.2 | 6 | 7.1 | ||
Present | 193 | 91.5 | 13 | 92.9 | 1.000 | 128 | 90.8 | 78 | 92.9 | 0.588 |
Venous invasion | ||||||||||
Absent | 150 | 71.1 | 6 | 42.9 | 102 | 72.3 | 54 | 64.3 | ||
Present | 61 | 28.9 | 8 | 57.1 | 0.027 | 39 | 27.7 | 30 | 35.7 | 0.205 |
TNM sub-stage | ||||||||||
IIIA | 77 | 36.5 | 3 | 21.4 | 54 | 38.3 | 26 | 31.0 | ||
IIIB | 69 | 32.7 | 3 | 21.4 | 41 | 29.1 | 31 | 36.9 | ||
IIIC | 55 | 26.1 | 8 | 57.1 | 0.125 | 46 | 32.6 | 27 | 32.1 | 0.404 |
Tumor size (mm) | ||||||||||
≤ 60 | 112 | 53.1 | 3 | 21.4 | 84 | 59.6 | 31 | 36.9 | ||
> 60 | 99 | 46.9 | 11 | 78.6 | 0.027 | 57 | 40.4 | 53 | 63.1 | 0.001 |
Adjuvant chemotherapy | ||||||||||
Absent | 37 | 17.5 | 4 | 28.6 | 29 | 20.6 | 12 | 14.3 | ||
Present | 174 | 82.5 | 10 | 71.4 | 0.292 | 112 | 79.4 | 72 | 85.7 | 0.238 |
CAR | ||||||||||
Low (≤0.47) | 139 | 98.6 | 72 | 85.7 | ||||||
High (> 0.47) | 2 | 1.4 | 12 | 14.3 | < 0.001 | |||||
NLR | ||||||||||
Low (≤1.90) | 98 | 46.4 | 1 | 7.1 | 85 | 60.3 | 14 | 16.7 | ||
High (> 1.90) | 113 | 53.6 | 13 | 92.9 | 0.004 | 56 | 39.7 | 70 | 83.3 | < 0.001 |
PLR | ||||||||||
Low (≤172) | 139 | 65.9 | 2 | 85.7 | ||||||
High (> 172) | 72 | 34.1 | 12 | 85.7 | < 0.001 | |||||
PNI | ||||||||||
Low (≤45.6) | 78 | 37.0 | 12 | 85.7 | 37 | 26.2 | 53 | 63.1 | ||
High (> 45.6) | 133 | 63.0 | 2 | 14.3 | < 0.001 | 104 | 73.8 | 31 | 36.9 | < 0.001 |
GPS | ||||||||||
0 | 171 | 81.0 | 0 | 0 | 115 | 81.6 | 56 | 66.7 | ||
1/2 | 40 | 19.0 | 14 | 100 | < 0.001 | 26 | 18.4 | 28 | 33.3 | 0.011 |
PI | ||||||||||
0 | 205 | 97.2 | 0 | 0 | 135 | 95.7 | 70 | 83.3 | ||
1/2 | 6 | 2.8 | 14 | 100 | < 0.001 | 6 | 4.3 | 14 | 16.7 | 0.002 |
Recurrence | ||||||||||
Absent | 113 | 53.6 | 4 | 28.6 | 80 | 56.7 | 37 | 44.0 | ||
Present | 98 | 46.4 | 10 | 71.4 | 0.097 | 61 | 43.3 | 47 | 56.0 | 0.065 |