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Table 1 Univariate analyses of prognostic factors for OS of stage III gastric cancer

From: Clinical significance of prognostic inflammation-based and/or nutritional markers in patients with stage III gastric cancer

Variables5-year OS (%)No. of patientsUnivariate
n%HR (95% CI)p value
Total48.7225100  
Age (years)
  ≤ 6854.011752.01 
  > 6842.810848.01.643 (1.164–2.319)0.005
Sex
 Male47.314765.31 
 Female51.27834.71.188 (0.823–1.715)0.357
BMI (kg/m2)
 Low (≤ 21.9)46.711450.71 
 High (>  21.9)50.611149.30.950 (0.674–1.339)0.771
Performance status
 052.116774.21 
 1–339.15825.81.606 (1.109–2.325)0.012
Location
 Upper/Middle/Lower50.720992.91 
 Whole20.6167.11.334 (1.092–1.630)0.005
Macroscopic type
 Type 0/1/256.96127.11 
 Type 3/4/545.616472.91.145 (0.774–1.693)0.497
Operative procedure
 Distal gastrectomy59.711752.01 
 Total gastrectomy36.910848.01.835 (1.295–2.600)0.001
Lymph node dissection
 D149.83214.21 
 D248.619385.80.911 (0.553–1.500)0.713
Histology
 Differentiated54.09743.11 
 Undifferentiated44.412856.91.198 (0.846–1.697)0.308
Lymphatic invasion
 Absent57.9198.41 
 Present47.820691.61.174 (0.633–2.177)0.611
Venous invasion
 Absent50.315669.31 
 Present44.86930.71.193 (0.830–1.716)0.340
TNM sub-stage
 IIIA62.28035.610.011
 IIIB45.47232.01.579 (1.030–2.420)0.036
 IIIC36.27332.41.908 (1.242–2.931)0.003
Tumor size (mm)
  ≤ 6055.911551.11 
  > 6040.911048.91.534 (1.086–2.166)0.015
Adjuvant chemotherapy
 Absent40.14118.21 
 Present50.618481.80.575 (0.382–0.865)0.008
CAR
 Low (≤ 0.47)50.621193.81 
 High (>  0.47)21.4146.22.844 (1.561–5.181)0.001
NLR
 Low (≤ 1.90)58.09944.01 
 High (>  1.90)41.212656.01.400 (0.986–1.988)0.060
PLR
 Low (≤ 172)53.214162.71 
 High (>  172)40.98437.31.376 (0.970–1.953)0.074
PNI
 Low (≤ 45.6)39.09040.01 
 High (>  45.6)54.913560.00.730 (0.517–1.031)0.074
GPS
 051.117176.01 
 1/241.15424.01.463 (0.992–2.156)0.055
PI
 050.120591.11 
 1/235.0208.91.592 (0.914–2.773)0.101
  1. BMI body mass index, PS performance status, TNM tumor-node-metastasis, CAR C-reactive protein/Albumin ratio, NLR neutrophil to lymphocyte ratio, PLR platelet to lymphocyte ratio, PNI Prognostic Nutritional Index, GPS Glasgow Prognostic Score, PI prognostic index